  {"id":25059,"date":"2024-06-25T15:19:53","date_gmt":"2024-06-25T07:19:53","guid":{"rendered":"https:\/\/www.curtin.edu.au\/news\/?post_type=media-release&#038;p=25059"},"modified":"2024-06-25T15:19:55","modified_gmt":"2024-06-25T07:19:55","slug":"funding-boost-for-curtin-tool-to-predict-chemo-effectiveness","status":"publish","type":"media-release","link":"https:\/\/www.curtin.edu.au\/news\/media-release\/funding-boost-for-curtin-tool-to-predict-chemo-effectiveness\/","title":{"rendered":"Funding boost for Curtin tool to predict chemo effectiveness"},"content":{"rendered":"\n<p>Âé¶¹Ö±²¥ research to develop an early diagnosis tool predicting how cancer patients will respond to chemotherapy has received a funding boost of almost half a million dollars through the Innovation Seed Fund 2023-24.<\/p>\n\n\n\n<p>Led by Dr Yu Yu from Curtin Medical School and the Curtin Health Innovation Research Institute, the project seeks to create a diagnostic test to identify patients who will benefit from platinum-based chemotherapy, which is commonly used in combatting advanced cancers, but often has poor outcomes.<\/p>\n\n\n\n<p>Dr Yu said ineffective therapy affects up to 1,500 people in WA yearly and more than two million globally.<\/p>\n\n\n\n<p>\u201cUnfortunately, up to half of all patients do not respond to platinum-based chemotherapy and the goal of this project is to provide clinicians with a tool that accurately predicts responses using biopsies at the onset of treatment,\u201d Dr Yu said.<\/p>\n\n\n\n<p>\u201cThis diagnostic test, known as ChemoDx, will enhance clinical decision-making, reduce unnecessary adverse effects and potentially improve survival rates by paving the way for tailored first-line treatments.\u201d<\/p>\n\n\n\n<p>Âé¶¹Ö±²¥ Deputy Vice-Chancellor Research Professor Melinda Fitzgerald congratulated Dr Yu and her team on the successful funding outcome.<\/p>\n\n\n\n<p>\u201cThis important research addresses a critical gap in cancer care and has the potential to transform cancer treatment making a real difference to people\u2019s lives,\u201d Professor Fitzgerald said.<\/p>\n\n\n\n<p>\u201cSupport from the Innovation Seed Fund reinforces Curtin\u2019s ongoing commitment to pioneering research that addresses critical health issues and allows our best minds to excel in their field.\u201d<\/p>\n\n\n\n<p>The project, titled <em>\u201cEarly Detection of Platinum-Chemotherapy Drug Response in Solid Tumour Biopsies\u201d<\/em>, focuses initially on ovarian cancer, one of the deadliest cancers with a high incidence of drug resistance and late-stage diagnosis.<\/p>\n\n\n\n<p>\u201cDrug resistance is a significant barrier to successful cancer treatment and the inability to predict platinum resistance exposes patients to chemotherapy side effects without therapeutic benefit and weakens the immune system,\u201d Dr Yu said.<\/p>\n\n\n\n<p>\u201cWe have identified biomarkers that predict the response of ovarian cancer to chemotherapy and the expected outcome is the development of a diagnostic tool that will improve cancer patient treatment worldwide.\u201d<\/p>\n\n\n\n<p>The Innovation Seed Fund, funded through the Western Australian Future Health Research and Innovation Fund, supports Western Australian innovators and early-stage start-up companies to develop and commercialise cutting-edge health and medical innovations.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Âé¶¹Ö±²¥ research to develop an early diagnosis tool predicting how cancer patients will respond 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